Oxford Nanopore Technologies Ltd

Publications related to sequencing DNA

'Strand sequencing'
Processive replication of single DNA molecules in a nanopore catalyzed by ph29 DNA polymerase. J. Am. Chem. Soc. 132 (50), 17961-72 (2010)

Identification of epigenetic DNA modifications with a protein nanopore. Chem. Commun. 46 (43), 8195-8197 (2010)

Replication of individual DNA molecules under electronic control using a protein nanopore. Nat. Nanotechnol. 5 (11), 798-806 (2010)

Nucleobase recognition in ssDNA at the central constriction of the alpha hemolysin pore. Nano Lett. 10 (9), 3633-3637 (2010)

Multiple base recognition sites in a biological nanopore: two heads are better than one. Angew. Chem. Int. Ed. 49 (3), 556-559 (2010)

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore. PNAS 106 (19), 7702-7707 (2009)

Sequence-specific detection of individual DNA strands using engineered nanopores. Nat. Biotechnol. 19 (7), 636-639 (2001)

'Exonuclease sequencing'

Continuous base identification for single-molecule nanopore DNA sequencing. Nat. Nanotechnol. 4 (4), 265-270 (2009)

Toward single molecule DNA sequencing. J. Am. Chem. Soc. 128 (5), 1705-1710 (2006)

Publications related to nanopores as biosensors

Single molecule detection of nitrogen mustards by covalent reaction within a protein nanopore. J. Am. Chem. Soc. 130 (21), 6813-6819 (2008)

Protein Nanopores with covalently attached molecular adapters. J. Am. Chem. Soc. 129 (151), 16142-16148 (2007)

Direct transfer of membrane proteins from bacteria to planar bilayers for rapid screening by single-channel recording. Nat. Chem. Biol. 2 (6), 314-318 (2006)

Stochastic sensing of enantiomers. J. Am. Chem. Soc. 128 (33), 10684-10685 (2006)

A genetically encoded pore for the stochastic detection of a protein kinase. Chem. BioChem. 7 (12), 1923-1927 (2006)

Direct introduction of single protein channels and pores into lipid bilayers. J. Am. Chem. Soc. 127 (18),6502-6503 (2005)

Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew. Chem. Int. Ed. 43 (7), 842-846 (2004)

Stochastic sensing of TNT with a genetically engineered pore. Chem. BioChem 6 (10), 1875-1881 (2005)

Kinetics of a reversible covalent-bond forming reaction observed at the single-molecule level. Angew. Chem. Int. Ed. 41 (19), 3707-3709 (2002)

Capture of a single molecule in a nanocavity. Science 291 (5504), 636-640 (2001)

Publications related to solid-state nanopores

Local electrical potential detection of DNA by nanowire-nanopore sensors.  Nature Nanotechnology 5 (12) doi:10.1038/nnano.2011.217

Hybrid pore formation by directed insertion of alpha hemolysin into solid-state nanopores. Nat. Nanotechnol. 5 (12), 874-877 (2010)

Ice Lithography for Nanodevices. Nano Lett. 10 (12), 5056-5059 (2010)

Graphene as a sub nanometre trans-electrode membrane. Nature 467 (7312), 190-193 (2010) Accompanying editorial by Professor Hagan Bayley

Recapturing and trapping single molecules with a solid-state nanopore. Nat. Nanotechnol. 2 (12), 775-779 (2007)

DNA conformation and base number simultaneously determined in a nanopore. Electrophoresis 28 (10), 3186-3192 (2007)

Review articles

Solid-state Nanopores Nat. Nanotechnol. 2 (4), 209-215 (2007)

Nanopore analysis of nucleic acids bound to exonucleases. Ann. Rev. Biophys. 39, 79-90 (2010)

The potential and challenges of nanopore sequencing. Nat. Biotechnol. 26 (10), 1146-1153 (2008) Download the article here from genome.gov

Sequencing single molecules of DNA. Curr. Opin. Chem. Biol. 10 (6), 628-637 (2006)

Stochastic sensors inspired by biology. Nature 413 (6852),226-230 (2001)

Stochastic sensing with protein pores. Adv. Mater. 12 (2), 139-142 (2000)

Building doors into cells. Sci. Am. 277 (3), 62-67 (1997)